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CURRENT PATHOLOGY IMAGING GUIDELINES
A. Neck
and thorax
B. Upper
abdomen
C. Genitourinary
system
D. Vascular
system
E. Central
nervous system
G. Extremities
H. Imaging resources
in Nuclear Medicine
- Musculoskeletal
system
- Respiratory
system
- Cardiovascular
system
- Urogenital
system
- Gastrointestinal
tract
- Central nervous
system
- Varied
scintigraphic techniques
- Targeted
studies - Oncology
- PET-CT imaging
- Radioactive
source treatment
1. Musculoskeletal system
Total body bone scintigraphic scanning:
- Bone metastases work-up and follow-up
- Local extension work-up of primary bone tumors
- Diagnosis and follow-up of Paget disease of bone
- Metabolic disorders (hypercalcemia,
hyperparathyroidism,…)
- Bone pain of unknown origin
Bone scintigraphy with dynamic phase:
- Diagnosis of traumatic lesions (fracture, bone
contusion...)
- Diagnosis of infectious/inflammatory disorders
(osteomyelitis, osteoarthritis,…)
- Diagnosis and follow-up of reflex sympathetic
dystrophy syndrome (Südeck)
- Diagnosis of prosthesis loosening/infection
- Diagnosis of aseptic necrosis (Perthes disease,
other osteochondroses)
2. Respiratory system
Ventilation & perfusion lung scan:
- Diagnosis and follow-up of lung embolism, pulmonary
hypertension
- Preoperative work-up and estimation of residual
capacity after resection
- Follow-up after lung transplantation
- Functional regional ventilation/perfusion ratio
3. Cardiovascular system
SPECT stress & resting myocardial tomoscintigraphy
(thallium or MIBI):
- Detection and work-up of coronary disease extension
- Depiction of residual ischemia after myocardial
infarct or after revascularisation
Isotopic resting ventriculography:
- Measurement of cardiac function and regional
contraction deficiencies
- Myocardial chemotherapy toxicity detection and
follow-up
4. Urogenital system
Simple isotopic nephrogram:
- Measurement of renal function - separate kidneys
- Residual function of a traumatised kidney
- Functional monitoring in paraplegic or tetraplegic
patients
- Renal graft monitoring
Isotopic nephrogram with furosemide test:
- Investigation of hydronephrosis or megaureter
- Obstructive uropathy
- Control after surgical repair
Isotopic nephrogram with captopril test:
- Arterial hypertension investigation
- Confirmation of renal artery stenosis
- Renal work-up before introduction of a prolonged
treatment with ACE inhibitors
DMSA renal scintigraphy:
- Suspicion of acute pyelonephritis
- Depiction of renal cortical scars after
pyelonephritis
- Scar imaging in malformative uropathy
- Evaluation of relative function of both kidneys
5. Gastrointestinal tract
Salivary glands scintigraphy:
- Functional evaluation of the salivary glands
- Obstruction of salivary ducts
Stomach solid and liquid contents clearing:
- Dysfunction of gastric emptying and motility
Hepatobiliary scintigraphy:
- Hepatobiliary function measurement
- Cholestasis investigation
- Diagnosis of a biliary fistula, particularly in
post-operative patients
- Suspicion of biliary tract atresia
Labeled red blood cells scintigraphy:
- Acute gastrointestinal tract hemorrhage localisation
- Investigation of an haemorrhage originating from
outside the gastrointestinal tract
Free Technetium scintigraphy:
- Meckel's diverticulum diagnosis
Milk-scan scintigraphy in a child:
- Gastro-oesophageal reflux diagnosis
- Bronchopulmonary aspiration detection
6. Central nervous system
Brain SPECT tomoscintigraphy:
- Neurodegenerative diseases
- Brain ischemic attack
- Localisation of a epileptogenic focus
- Diagnosis of brain tumors
- Dementia work-up
- Evaluation of AIDS-related diseases
- Functional vascular residual capacity test
(Acetazolamide test)
7. Varied scintigraphic techniques
Thyroid scintigraphy:
- Thyroid function test
- Thyroid nodule diagnosis
- Iodine organification defect diagnosis by
perchlorate test
- Functional thyroid disorders diagnosis
- Iodine extraction rate calculation before
radioiodine therapy
Localisation of infectious/inflammatory focus:
- Scintigraphy with antigranulocyte antibodies
- Scintigraphy with HIG (polyclonal Human
Immunoglobulin G )
- Gallium Scintigraphy
Lymphoscintigraphy :
- Sentinel lymph node localisation in case of
malignant melanoma
- Sentinel lymph node localisation for breast cancer
- Peripheral lymphatic backflow disorders
8. Targeted tests - Oncology
MIBG scintigraphy :
- Localisation of medullo-adrenal gland tumors
(pheochromocytoma)
- Neuroectodermic neoplasms work-up and follow-up
(neuroblastoma)
- Neuroendocrin tumors (gastro-entero-pancreatic,
pulmonary)
Octreotide scintigraphy:
- Neuroendocrin tumors (gastro-entero-pancreatic,
pulmonary)
- Small cell lung cancer
- Thyroid medullary cancer
Gallium scintigraphy:
- Hodgkin's lymphoma work-up and follow-up with early
recurrence detection
- Work-up and follow-up of non hodgkin lymphomas
MIBI scintigraphy:
- Parathyroid adenoma localisation
- Malignant melanoma dissemination work-up
- Mammary gland neoplasia
9. PET-CT imaging
PET-CT in oncology :
- Diagnosis of a solitary lung nodule
- Diagnosis between recurrence/residual tumor and
radionecrosis/scar tissue
- Treatment monitoring
- Radio-oncologic treatment planning
- Non small cell lung cancers (NSCLC)
- Otolaryngologic cancers
- Breast cancer
- Hodgkin's lymphoma and non hodgkin lymphomas
- Rectocolic cancer
- Esophagus cancer
- Malignant melanoma
- Germinal cell tumors in males
- Brain tumor diagnosis and follow-up
- Other tumors (ovaries, uterus, pancreas, sarcomas of
bone and soft parts, SCLC, mesothelioma, …)
Brain PET-CT:
- Epileptogenic focus localisation
- Preoperative brain tumor test
- Early tumor recurrence detection and differential
diagnosis from radionecrosis
- Dementia diagnosis
10. Radioactive source treatment (after medical
agreement)
- Palliative antalgic treatment of bone metastases
(breast, prostate):
- Strontium 89m
- Samarium 153 EDTMP
- Thyroid hyperfunction treatment: Iodine 131
Institut d'Imagerie Médicale - Clinique
de Genolier - CH-1272 Genolier
Dr Jean-Pierre Papazyan Tél: +41.22.366.94.84 - Fax:
+41.22.366.94.82
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